When ever you feel like you have no other choices. Just know that things can turn around when you least expect it. Whether the situation has to do with Work, School, Family or even Self. It will turn around. Trust me there were many tines when I felt like everything was going downhill. Everything also happens for a reason. Situation that may seem like shit and probably are shit will make you a better person.
I know this is short but I've been busy with classes.